Manufactured by Roche
Uses: Used as an add-on to control seizures instead of rectal diazepam
Common side effects: Dizziness, restlessness, headache
Remarks: The use of Midazolam instead of rectal Diazepam is very recent and you might find that doctors are not keen to prescribe it.
Product Info:
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Furthermore the information contained in these documents is accurate as of their specified date and may become out of date over time and thus should be considered current only as of the date stated. This information is not intended to be a substitute for the advice of a health care professional, or a recommendation for any particular treatment plan, and is not intended to supplement, modify or supercede the information provided in the product package insert with respect to the use of the product for medical purposes.
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Hypnovel 10mg-5ml Ampoules Technical Information (pdf)
Hypnovel 10mg-2ml Ampoules Technical Information (pdf)
Hypnovel 10mg-5ml Ampoules Summary of Product Charateristics (pdf)
Hypnovel 10mg-2ml Ampoules Summary of Product Charateristics (pdf)
FURTHER READING
1. A COMPARATIVE STUDY OF INTRAVENOUS AND INTRAMUSCULAR MIDAZOLAM IN PATIENTS WITH EPILEPSY - D.M Bell et al., Epilepsy Res.,10:183-190 1991
2. A RANDOMISED TRIAL COMPARING BUCCAL MIDAZOLAM TO RECTAL DIAZEPAM IN THE TREATMENT OF PROLONGED SEIZURES IN CHILDHOOD AND ADOLESCENCE R.C Scott et al., for a copy of this article please contact St.Piers or Lancet., 353:623-626 1999
3. MIDAZOLAM IN THE TREATMENT OF EPILEPTIC SEIZURES - S. Ghilain et al., J. Neurol. Neurosurg. Psychiatry 51:732 1988
4. A PHARMACOLOGIC EVALUATION OF MIDAZOLAM AS AN ANTIEPILEPTIC COMPOUND - S. Jawad et al., J. neurol. Neurosug. Psychiatry, 49:1050-1054 1986
5. CONTINUOUS MIDAZOLAM AS TREATMENT OF STATUS EPILEPTICUS - R.L Koul et al., Arch Dis Child., 76:445-448 1997
6. MIDAZOLAM IN THE TREATMENT OF STATUS EPILEPTICUS IN CHILDREN - R. Rivera et al., Crit Care Med., 21:991-994 1993
7. TREATMENT OF REFRACTORY GENERALIZED STATUS EPILEPTICUS WITH CONTINUOUS INFUSION OF MIDAZOLAM - J.M Parent et al., Neurology., 44:1837-1840 1994
8. MIDAZOLAM IN TREATMENT OF EPILEPTIC SEIZURES - E. Lahat et al., Pediatr. Neurol., 8:215-216 1992
9. COMPARISON OF MIDAZOLAM NASAL SPRAY TO NASAL DROPS FOR THE SEDATION OF CHILDREN - B. Ljung et al., J Nucl. Med Technol., 24:32-34 1996
10. THE USE OF CLOBAZAM, MIDAZOLAM AND NITRAZEPAM IN EPILEPSY - S.D Shorvon., Epilepsia., 39 (suppl.1):S15-S23 1998
11. CONCENTRATIONS AND ORAL EFFECTS OF ORAL MIDAZOLAM ARE GREATLY REDUCED IN PATIENTS TREATED WITH CARBAMAZEPINE AND PHENYTOIN - J.T. Backman et al., Epilepsia., 37:253-257 1996
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